Gut Health
A gut that performs.
Gut & Microbiome
What's happening
The gut-brain axis is real biology, not a marketing line. Mood, immunity, cognitive load, and recovery all involve communication between the microbiome, the enteric nervous system, and the CNS. Bacillus coagulans GBI-30, 6086 (BC30) is a heat-stable spore-former. The spore survives gastric acid and bile transit, germinating in the small intestine. The Dolin RCTs covered abdominal symptoms; the Baron RCT covered immune response to viral challenge; the Jäger RCT covered exercise-induced muscle damage recovery in resistance-trained men. Tributyrin is the triglyceride form of butyric acid. Pancreatic lipase cleaves it distally, releasing butyrate where colonocytes use it as their principal energy substrate. Ginger gingerols modulate COX-2 and 5-LOX enzymes and stimulate gastric motility via enteric cholinergic effects.
Evidence. Peer-reviewed, PubMed-verified
Bacillus coagulans GBI-30, 6086. Dolin abdominal pain/bloating RCT (Dolin 2009a, Postgrad Med); Dolin diarrhoea-symptoms RCT (Dolin 2009b, Methods Find Exp Clin Pharmacol); Baron viral-challenge immune response (Baron 2009, Postgrad Med); Jäger exercise recovery (Jäger 2016, PeerJ).
Tributyrin. Canani butyrate intestinal-health review (Canani 2011, World J Gastroenterol); Louis microbiota-SCFA pathway (Louis 2014, Nat Rev Microbiol); Duysburgh human gut simulation model (Duysburgh 2025, Front Nutr).
Ginger. Black post-exercise pain RCT (Black 2010, J Pain); Mao bioactive compounds review (Mao 2019, Foods); Daily dysmenorrhoea systematic review (Daily 2015, Pain Med).
Full register: /pages/research.
How Rōnin addresses it
| Ingredient | Dose | Role |
|---|---|---|
| Bacillus coagulans GBI-30 | 2B CFU | End-of-life potency; strain-specific BC30 trial base |
| Tributyrin | 500mg | Encapsulated; distal-colon butyrate delivery |
| Gum Arabic (Acacia fibre) | 1,919mg | ≥85% soluble dietary fibre; prebiotic SCFA substrate |
| Algal DHA | 250mg DHA | SPM substrate; resolution-of-inflammation lipid mediators |
| Ginger Root Extract | 500mg | ≥5% gingerols; supports normal digestive function |
| Zinc Bisglycinate | 16mg elemental | [GB-NHC] protection of cells from oxidative stress |
All ingredients listed are included in the Rōnin Daily Formula at the stated doses. One daily scoop.