Hormonal Health
Drive that endures.
Hormonal Health
What's happening
Testosterone and thyroid function are both nutrient-dependent processes. Zinc is a cofactor for the steroidogenic enzymes in testicular Leydig cells and the upstream pituitary signalling. Vitamin D3 functions more as a steroid hormone than a vitamin. VDR (vitamin D receptor) is expressed in the gonads. The Pilz 2011 RCT (54 overweight men with low baseline D status, 3,332 IU/day for 12 months) showed serum total testosterone rose from 10.7 → 13.4 nmol/L vs no change on placebo; the effect should be read as status normalisation in a sub-optimal subgroup. Selenium is the cofactor for the iodothyronine deiodinases that convert T4 to bioactive T3. Without adequate selenium, thyroid output is impaired regardless of iodine intake. UK selenium soils are low; supplementation matters.
Evidence. Peer-reviewed, PubMed-verified
Vitamin D3. Pilz testosterone RCT, 54 men, 12 months (Pilz 2011, Horm Metab Res); Holick NEJM canonical (Holick 2007, N Engl J Med); Tripkovic D3 vs D2 meta-analysis (Tripkovic 2012, Am J Clin Nutr). [GB-NHC] Vitamin D contributes to maintenance of normal muscle function · maintenance of normal bones (≥1.5 µg/day; Rōnin 50 µg).
Zinc. Haase & Rink zinc-immune signalling (Haase 2014, BioFactors); Wessels gatekeeper review (Wessels 2017, Nutrients). [GB-NHC] Zinc contributes to maintenance of normal testosterone levels in the blood (≥1.5 mg/day; Rōnin 16 mg).
Selenium. Rayman Lancet review (Rayman 2012, Lancet); Fairweather-Tait comprehensive review (Fairweather-Tait 2011, Antioxid Redox Signal). [GB-NHC] Selenium contributes to normal thyroid function · normal spermatogenesis (≥8.25 µg/day; Rōnin 100 µg).
Full register: /pages/research.
How Rōnin addresses it
| Ingredient | Dose | Role |
|---|---|---|
| Vitamin D3 | 2,000 IU | Algae-derived; [GB-NHC] immune + muscle + bones |
| Zinc Bisglycinate | 16mg elemental | [GB-NHC] maintenance of normal testosterone levels |
| Selenium | 100µg | L-selenomethionine; [GB-NHC] thyroid + spermatogenesis |
| Magnesium Bisglycinate | 200mg elemental | [GB-NHC] normal psychological function + nervous system |
| Vitamin K2 MK-7 | 180µg | All-trans ≥98%; D3 synergy on bone-vascular calcium |
| Vitamin B6 (P-5-P) | 2.8mg | [GB-NHC] regulation of hormonal activity |
| Iodine | 150µg | UK NRV; [GB-NHC] normal production of thyroid hormones |
All ingredients listed are included in the Rōnin Daily Formula at the stated doses. One daily scoop.