Pillar — Immune Defence

60%

of UK adults are vitamin D deficient by winter.

Public Health England · 2016

The gap

60% of UK adults are vitamin D deficient by winter. Your immune system depends on a year-round floor — not a panic supplement when you feel the first sniffle.

The evidence

  1. 12%

    lower overall ARTI odds in 11,321-subject IPD meta-analysis; effect stronger in baseline-deficient adults on daily dosing

    Martineau · BMJ 2017

  2. 500 mg

    vitamin C achieves plasma saturation — higher doses are excreted

    Padayatty · Ann Intern Med 2004

  3. 70%

    of immune cells reside in the gut-associated lymphoid tissue (GALT)

    Vighi · Clin Exp Immunol 2008

What KōJō provides

Three inputs, dosed at the level the research used.

  1. Ingredient 1

    2,000 IU

    Vitamin D3 (algae-derived)

    Daily winter floor for UK adults. The dose used in the Martineau IPD meta-analysis (n=11,321) — overall 12% lower ARTI odds, with stronger effect in baseline-deficient adults receiving daily dosing.

  2. Ingredient 2

    500 mg

    Vitamin C

    L-ascorbic acid at the plasma-saturation dose. Collagen synthesis, immune cell function, non-haem iron absorption.

  3. Ingredient 3

    16 mg + 600 mg

    Zinc + NAC

    Zinc bisglycinate (quick-response antiviral cofactor) plus N-acetyl cysteine (glutathione precursor). The cellular-resilience pair.

What to expect

It compounds. Give it the time.

  1. Week 1–2

    Vitamin C plasma saturates.

    Steady-state plasma ascorbate reached. Zinc loads quickly; NAC starts supporting glutathione synthesis.

  2. Month 2

    D3 serum levels rise.

    25(OH)D climbs above sufficiency threshold (75 nmol/L). The Martineau-trial floor is built.

  3. Through winter

    Year-round resilience.

    You stop noticing how often everyone else gets sick. Not zero — just less, and shorter when it happens.

Less noise. More proof.

Every dose published. Every ingredient sourced.

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