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Stress & Cortisol

Composed under pressure.

Stress & Cortisol

What's happening

Cortisol is the body's principal glucocorticoid. A measurable circulating hormone with a daily rhythm and an acute response curve to physical and psychological load. Chronically elevated cortisol disrupts sleep architecture, depletes magnesium and B-vitamins faster than diet replaces them, and blunts the parasympathetic system. Rhodiola Rosea's active compounds (rosavins + salidroside) modulate the HPA-axis cortisol response in the Olsson stress-related-fatigue RCT. L-Theanine increases alpha-wave EEG activity, the relaxed-but-alert state, without sedation. Glycine has placebo-controlled-RCT evidence for improving subjective sleep quality and reducing next-morning sleepiness in volunteers with poor sleep.

Evidence. Peer-reviewed, PubMed-verified

Rhodiola Rosea. Olsson stress-related fatigue RCT, 60 adults at 576 mg/day SHR-5 for 28 days (Olsson 2009, Planta Med); Shevtsov dose-finding RCT in 161 cadets (Shevtsov 2003, Phytomedicine); Ishaque systematic review of 11 RCTs (Ishaque 2012, BMC Complement Altern Med).

L-Theanine. Owen theanine + caffeine attention RCT (Owen 2008, Nutr Neurosci); Hidese 200 mg/day × 4 weeks RCT in healthy adults (Hidese 2019, Nutrients); Nobre mental-state characterisation (Nobre 2008, Asia Pac J Clin Nutr).

Magnesium. de Baaij comprehensive review (de Baaij 2015, Physiol Rev); Schuchardt bisglycinate bioavailability (Schuchardt 2017, Curr Nutr Food Sci). [GB-NHC] Magnesium contributes to normal psychological function · reduction of tiredness and fatigue (≥56.25 mg/day; Rōnin delivers 200 mg).

Full register: /pages/research.

How Rōnin addresses it

Ingredient Dose Role
Rhodiola Rosea 350mg ≥3% rosavins, ≥1% salidroside; HPA-axis modulation research
L-Theanine 200mg Suntheanine ≥98% L-isomer; alpha-wave EEG activity
Glycine 2,000mg Inhibitory neurotransmitter; glutathione precursor
Magnesium Bisglycinate 200mg elemental [GB-NHC] normal psychological function · tiredness/fatigue
Vitamin B6 (P-5-P) 2.8mg [GB-NHC] normal psychological function · hormonal regulation
Vitamin C 500mg Adrenal cortex concentrates ascorbate; [GB-NHC] tiredness/fatigue
Vitamin B5 (Pantothenic acid) 6mg CoA precursor; [GB-NHC] normal mental performance
Build Your Stack. £69 or £58.65/month

All ingredients listed are included in the Rōnin Daily Formula at the stated doses. One daily scoop.