CARDIOVASCULAR & METABOLIC HEALTH - RŌNIN V4.1
Why 300mg of Potassium?
The primary intracellular electrolyte. Required for the Na⁺/K⁺-ATPase pump that drives all cellular membrane potential - nerve conduction, muscle contraction, cardiac rhythm. UK adults average ~70% of the adequate intake. Balanced with sodium from Himalayan salt.
- CATEGORY
- Electrolytes
- DOSE
- 300mg
- FORM
- Food grade - pharmaceutical purity
- EVIDENCE LEVEL
- Strong - extensive human and clinical data
How Potassium works
Potassium (K⁺) is maintained at 140 mEq/L intracellularly vs ~4 mEq/L extracellularly - a 35:1 gradient maintained by the Na⁺/K⁺-ATPase pump at the cost of ~30% of total cellular ATP production. This gradient drives the resting membrane potential of all excitable cells (neurons, cardiac myocytes, skeletal muscle fibres). Potassium is also an intracellular enzyme cofactor, required for pyruvate kinase and other glycolytic enzymes.
UK dietary surveys show median potassium intake of approximately 3,000mg/day - well below the EFSA Adequate Intake of 3,500mg/day. Low potassium intake reduces the kidney's ability to excrete sodium, which can affect blood pressure regulation. The 400mg in this formula contributes approximately 11% of the AI.
Key benefits
- Primary intracellular electrolyte - maintains membrane potential in all cells
- Required for Na⁺/K⁺-ATPase pump (uses ~30% of cellular ATP)
- UK adults ~70% of adequate intake on average
- Low intake independently associated with elevated blood pressure
- Balanced with sodium from Himalayan salt
The researchGB-NHC
Peer-reviewed human trials supporting this ingredient at this dose.
- Effect of increased potassium intake on cardiovascular risk factors and disease: systematic review and meta-analyses.PubMed →
- The impact of baseline potassium intake on the dose-response relation between sodium reduction and blood pressure change.PubMed →
- Community-level dietary intake of sodium, potassium, and sodium-to-potassium ratio as a global public health problem.PubMed →
IN THE FORMULA
Potassium
300mg
Potassium chloride
WHEN TO TAKE IT
Any time of day with food. Potassium is the primary intracellular electrolyte - consistent daily intake maintains the Na⁺/K⁺ gradient across all cell membranes. Take with food to avoid mild GI sensitivity.