Bacillus coagulans GBI-30, 6086

2 billion CFU

The only probiotic strain with published human RCT data for gut and immune outcomes. Ganeden BC30 spores survive manufacturing and gastric acid - conditions that destroy most conventional probiotics before they reach the colon.

Category Gut & Microbiome
Dose 2 billion CFU
Form Spore form - Ganeden BC30 strain
Evidence Level Strong - strain-specific human RCTs

Mechanism

Most probiotic strains are destroyed during manufacturing (heat, pressure, pH) or by stomach acid before reaching the colon. Bacillus coagulans GBI-30, 6086 is a spore-forming probiotic: in its spore state, it is effectively inert and survives both manufacturing conditions and gastric transit. On reaching the small intestine, the spore germinates into the active vegetative form.

The strain designation GBI-30, 6086 is critical. Probiotic research is strain-specific - results from one strain cannot be extrapolated to other strains of the same species. The GBI-30 6086 strain has specific published human RCT evidence for gut symptom relief, immune function, and protein utilisation. Generic "Bacillus coagulans" products do not share this evidence base.

Key Benefits

  • Survives manufacturing and gastric acid - reaches the colon intact
  • Strain-specific human RCT evidence (GBI-30, 6086 only)
  • Supports gut barrier integrity and bowel regularity
  • Clinically studied for immune support and protein digestion
  • No refrigeration required

The Research

Peer-reviewed human trials supporting this ingredient at this dose.

Dolin BJ. (2009). Methods Find Exp Clin Pharmacol. 31(10):655-9.Effects of a proprietary Bacillus coagulans preparation on symptoms of diarrhea-predominant irritable bowel syndrome.PubMed →
Hun L. (2009). Postgrad Med. 121(2):119-24.Bacillus coagulans significantly improved abdominal pain and bloating in patients with IBS.PubMed →
Baron M. (2009). Postgrad Med. 121(2):114-8.A patented strain of Bacillus coagulans increased immune response to viral challenge.PubMed →
Jäger R, et al. (2016). PeerJ. 4:e2276.Probiotic Bacillus coagulans GBI-30, 6086 reduces exercise-induced muscle damage and increases recovery.PubMed →
In the formula

Bacillus coagulans GBI-30, 6086

2 billion CFU

Spore form - Ganeden BC30 strain

When to take it

Any time of day. The spore form is heat-stable and survives manufacturing, storage, and gastric acid - no refrigeration or timing requirements.

Works well with

Gut & Microbiome Tributyrin 500mg Greens Moringa Leaf Powder 2,500mg Micronutrients Vitamin D3 2,000 IU
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