Why 750mcg RAE of Mixed Carotenoids?

How Mixed Carotenoids works

The four carotenoids in this formula serve complementary roles: beta-carotene converts to vitamin A (retinol) as needed; lycopene accumulates in the prostate and vascular endothelium with antioxidant and anti-atherogenic properties; lutein and zeaxanthin concentrate in the macula of the retina as macular pigment optical density (MPOD), filtering high-energy blue light and reducing photooxidative stress.

Mixed carotenoids have a critical safety advantage over isolated beta-carotene: high-dose isolated beta-carotene has been studied with mixed safety outcomes in smokers in smokers in the ATBC and CARET trials. Mixed carotenoids - as found in whole foods - have no such association. The matrix also allows competitive absorption, preventing any single carotenoid from dominating at the expense of others.

Key benefits

• Beta-carotene: provitamin A (converts to retinol as needed)
• Lycopene: antioxidant in vascular endothelium and prostate tissue
• Lutein + zeaxanthin: macular pigment for visual health
• Mixed form avoids isolated beta-carotene risks in smokers
• Synergistic absorption in natural carotenoid matrix

The researchGB-NHC

Peer-reviewed human trials supporting this ingredient at this dose.

1. Stahl W, Sies H. (2012). Mol Nutr Food Res. 56(2):287-95.Photoprotection by dietary carotenoids: concept, mechanisms, evidence and future development.PubMed →
2. Kruger J, et al. (2024). Eur J Nutr. advance access.Low β-carotene bioaccessibility and bioavailability from high fat, dairy-based meal.PubMed →
3. Chen X, et al. (2024). Biogerontology. 26(1):24.Associations between dietary carotenoid and biological age acceleration: NHANES 2009-2018.PubMed →

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