ANTIOXIDANT & CELLULAR DEFENCE - RŌNIN V4.1
Why 15mg of Vitamin E?
Full-spectrum tocopherols - not isolated alpha-tocopherol. Gamma and delta tocopherols have distinct anti-inflammatory activity complementary to alpha. Protects polyunsaturated fatty acid membranes (including DHA) from lipid peroxidation.
- CATEGORY
- Micronutrients
- DOSE
- 15mg
- FORM
- D-alpha plus beta, gamma, delta tocopherols - natural matrix
- EVIDENCE LEVEL
- Strong - EFSA approved health claims
How Vitamin E works
Vitamin E tocopherols are the primary fat-soluble chain-breaking antioxidants, interrupting the lipid peroxidation cascade in cell membranes by donating a hydrogen atom to lipid peroxy radicals - preventing the chain reaction from propagating to adjacent polyunsaturated fatty acids. The DHA in this formula is particularly vulnerable to peroxidation without adequate vitamin E protection.
Mixed tocopherols are chosen over isolated alpha-tocopherol for two reasons: gamma-tocopherol has unique electrophilic nitrating activity - trapping reactive nitrogen species that alpha-tocopherol cannot neutralise; and supplementation with alpha-tocopherol alone can displace and deplete gamma-tocopherol from tissues. The full-spectrum matrix provides complementary, non-competing antioxidant coverage.
Key benefits
- Primary fat-soluble chain-breaking antioxidant in membranes
- Protects polyunsaturated DHA from lipid peroxidation
- Gamma-tocopherol traps reactive nitrogen species
- Mixed form prevents alpha from depleting gamma in tissue
- 15mg = 100% NRV
The researchGB-NHC
Peer-reviewed human trials supporting this ingredient at this dose.
- Natural forms of vitamin E: metabolism, antioxidant, and anti-inflammatory activities and the role in disease prevention and therapy.PubMed →
- Vitamin E therapy beyond cancer: tocopherol versus tocotrienol.PubMed →
- Comparing vitamin E tocotrienol-rich fraction versus α-tocopherol on gene expression in healthy older adults.PubMed →
IN THE FORMULA
Vitamin E
15mg
Mixed tocopherols (d-alpha, beta, gamma, delta)
WHEN TO TAKE IT
Take with food containing fat - vitamin E is fat-soluble. The mixed tocopherol matrix provides broader antioxidant coverage than alpha-tocopherol alone.