Vitamin E (Mixed Tocopherols)

15mg

Full-spectrum tocopherols - not isolated alpha-tocopherol. Gamma and delta tocopherols have distinct anti-inflammatory activity complementary to alpha. Protects polyunsaturated fatty acid membranes (including DHA) from lipid peroxidation.

Category Micronutrients
Dose 15mg
Form D-alpha plus beta, gamma, delta tocopherols - natural matrix
Evidence Level Strong - EFSA approved health claims

Mechanism

Vitamin E tocopherols are the primary fat-soluble chain-breaking antioxidants, interrupting the lipid peroxidation cascade in cell membranes by donating a hydrogen atom to lipid peroxy radicals - preventing the chain reaction from propagating to adjacent polyunsaturated fatty acids. The DHA in this formula is particularly vulnerable to peroxidation without adequate vitamin E protection.

Mixed tocopherols are chosen over isolated alpha-tocopherol for two reasons: gamma-tocopherol has unique electrophilic nitrating activity - trapping reactive nitrogen species that alpha-tocopherol cannot neutralise; and supplementation with alpha-tocopherol alone can displace and deplete gamma-tocopherol from tissues. The full-spectrum matrix provides complementary, non-competing antioxidant coverage.

Key Benefits

  • Primary fat-soluble chain-breaking antioxidant in membranes
  • Protects polyunsaturated DHA from lipid peroxidation
  • Gamma-tocopherol traps reactive nitrogen species
  • Mixed form prevents alpha from depleting gamma in tissue
  • 15mg = 100% NRV

The Research

Peer-reviewed human trials supporting this ingredient at this dose.

Jiang Q. (2014). Free Radic Biol Med. 72:76-90.Natural forms of vitamin E: metabolism, antioxidant, and anti-inflammatory activities and the role in disease prevention and therapy.PubMed →
Peh HY, et al. (2016). Pharmacol Ther. 162:152-69.Vitamin E therapy beyond cancer: tocopherol versus tocotrienol.PubMed →
Ghani SMA, et al. (2019). Clinics (Sao Paulo). 74:e688.Comparing vitamin E tocotrienol-rich fraction versus α-tocopherol on gene expression in healthy older adults.PubMed →
In the formula

Vitamin E (Mixed Tocopherols)

15mg

D-alpha plus beta, gamma, delta tocopherols - natural matrix

When to take it

Take with food containing fat - vitamin E is fat-soluble. The mixed tocopherol matrix provides broader antioxidant coverage than alpha-tocopherol alone.