Why 350mg of Rhodiola Rosea?

How Rhodiola Rosea works

Rhodiola rosea is a well-characterised adaptogen - a compound that increases non-specific resistance to stress without impairing normal function. Its primary mechanism involves modulation of the HPA (hypothalamic-pituitary-adrenal) axis: blunting the cortisol stress response while maintaining alertness and cognitive function.

The European Medicines Agency (EMA) has assessed Rhodiola for mental fatigue and stress, giving it a positive opinion based on clinical evidence. The standardisation ratio is critical for efficacy - the two active compound classes (rosavins and salidroside) must both be verified by HPLC. Products with only rosavin standardisation are incomplete.

Key benefits

• Traditional Scandinavian and Siberian adaptogen, used for centuries
• Standardised to ≥3% rosavins and ≥1% salidroside. The most-studied markers
• Supports cognitive performance under stressful conditions
• EMA-assessed for traditional use in stress and mental fatigue
• Effects accumulate with consistent daily use

The research

Peer-reviewed human trials supporting this ingredient at this dose.

1. Olsson EM, et al. (2009). Planta Med. 75(2):105-12.A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract SHR-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue.PubMed →
2. Shevtsov VA, et al. (2003). Phytomedicine. 10(2-3):95-105.A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work.PubMed →
3. Ishaque S, et al. (2012). BMC Complement Altern Med. 12:70.Rhodiola rosea for physical and mental fatigue: a systematic review.PubMed →
4. Anghelescu IG, et al. (2018). Int J Psychiatry Clin Pract. 22(4):242-52.Stress management and the role of Rhodiola rosea: a review.PubMed →

Works well with