Why 300mg of Bacopa Monnieri?

How Bacopa Monnieri works

Bacopa monnieri (brahmi) is a well-characterised nootropic Ayurvedic herb whose active compounds - bacosides A and B - enhance kinase activity in the hippocampus, facilitating synaptic plasticity and the consolidation of new memories. Unlike acute stimulants, Bacopa's mechanism requires weeks of daily exposure to accumulate in tissue; 8-12 weeks is the typical trial duration used in clinical research.

A 2014 systematic review by Kongkeaw et al. assessed 9 double-blind RCTs and found consistent, significant improvements in memory free recall, retention, and cognitive performance. Bacopa also has adaptogenic properties - animal and human data suggest modulation of the stress-cortisol response, complementing Rhodiola in this formula.

Key benefits

• Traditionally used in Ayurvedic preparations for over 2,000 years
• Research has examined bacosides A and B in the Bacopa family
• Effects accumulate over 8-12 weeks of daily use
• Adaptogenic - modulates stress-cortisol response
• ≥55% bacosides: full-spectrum, highest-grade standardisation

The research

Peer-reviewed human trials supporting this ingredient at this dose.

1. Kongkeaw C, et al. (2014). J Ethnopharmacol. 151(1):528-35.Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract.PubMed →
2. Stough C, et al. (2001). Psychopharmacology. 156(4):481-4.The chronic effects of an extract of Bacopa monnieri (Brahmi) on cognitive function in healthy human subjects.PubMed →
3. Lopresti AL, et al. (2025). Clin Drug Investig. 45(12).The effects of a Bacopa monnieri extract on cognition, stress and fatigue in healthy adults.PubMed →

Works well with