Copper Bisglycinate
Required for ceruloplasmin (iron transport), cytochrome c oxidase (mitochondrial Complex IV), and Cu/Zn-superoxide dismutase. Balanced with zinc at the physiologically-correct 16:1 ratio. Bisglycinate form for superior absorption without GI irritation.
Mechanism
Copper is an obligate cofactor for several critical enzymes: ceruloplasmin (which oxidises Fe²⁺ to Fe³⁺ for iron transport in plasma); cytochrome c oxidase (the terminal enzyme in the mitochondrial electron transport chain, Complex IV); Cu/Zn-superoxide dismutase (the primary cytoplasmic antioxidant enzyme); and lysyl oxidase (required for collagen and elastin cross-linking in connective tissue).
The 16:1 zinc-to-copper ratio in this formula (16mg zinc : 1mg copper) reflects the physiological balance in which these competing minerals must be provided. High-dose zinc supplementation in isolation - a common pattern in zinc-only supplements - significantly impairs copper absorption and can produce copper deficiency over time.
Key Benefits
- Cofactor for cytochrome c oxidase (mitochondrial Complex IV)
- Required for iron transport via ceruloplasmin
- Component of Cu/Zn-SOD - primary cytoplasmic antioxidant enzyme
- Balanced with zinc at physiologically-correct 16:1 ratio
- Bisglycinate form: superior absorption, no GI irritation
The Research
Peer-reviewed human trials supporting this ingredient at this dose.
Copper Bisglycinate
2mgChelated - Albion TRAACS grade
Any time of day with food. Provided at the physiologically-correct 16:1 zinc-to-copper ratio alongside the 16mg zinc in this formula. High-dose zinc alone depletes copper.