Why 6mg of Vitamin B5?

How Vitamin B5 works

Pantothenic acid is the obligate precursor for Coenzyme A (CoA) synthesis - CoA is one of the most functionally central molecules in metabolism. As acetyl-CoA, it feeds the Krebs cycle; as acyl-CoA, it drives fatty acid oxidation and synthesis; as cholesterol-CoA, it initiates steroid hormone synthesis. Every cell in the body requires CoA for energy production.

B5 is also the precursor to acyl carrier protein (ACP), required for de novo fatty acid synthesis in the cytoplasm. While dietary deficiency is uncommon, metabolically active individuals with high energy throughput - exercise, cognitive load, stress - increase CoA turnover and hence B5 demand.

Key benefits

• Obligate precursor to Coenzyme A - central to all energy metabolism
• Required for Krebs cycle (acetyl-CoA), fatty acid oxidation, and steroid synthesis
• Precursor to acyl carrier protein (fatty acid synthesis)
• Supports steroid hormone and CoQ10 biosynthesis
• 6mg = 100% NRV

The researchGB-NHC

Peer-reviewed human trials supporting this ingredient at this dose.

1. Tahiliani AG, Beinlich CJ. (1991). Vitam Horm. 46:165-228.Pantothenic acid in health and disease.PubMed →
2. Wedman JJ, et al. (2024). J Inherit Metab Dis. 47(1):69-86.Impaired CoA homeostasis in cardiac dysfunction and benefits of boosting CoA production with vitamin B5.PubMed →
3. Freese R, et al. (2023). Food Nutr Res. 67.Pantothenic acid. A scoping review for Nordic Nutrition Recommendations 2023.PubMed →
4. Miallot R, et al. (2023). Eur J Immunol. 53(10):e2350435.The vitamin B5/coenzyme A axis: a target for immunomodulation?PubMed →

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