Pantothenic Acid (B5)
Required for Coenzyme A synthesis - CoA is the central metabolic hub involved in the Krebs cycle, fatty acid oxidation, and steroid hormone synthesis. Also essential for the synthesis of coenzyme A itself, acetyl-CoA, and acyl carrier protein. 6mg = 100% NRV.
Mechanism
Pantothenic acid is the obligate precursor for Coenzyme A (CoA) synthesis - CoA is one of the most functionally central molecules in metabolism. As acetyl-CoA, it feeds the Krebs cycle; as acyl-CoA, it drives fatty acid oxidation and synthesis; as cholesterol-CoA, it initiates steroid hormone synthesis. Every cell in the body requires CoA for energy production.
B5 is also the precursor to acyl carrier protein (ACP), required for de novo fatty acid synthesis in the cytoplasm. While dietary deficiency is uncommon, metabolically active individuals with high energy throughput - exercise, cognitive load, stress - increase CoA turnover and hence B5 demand.
Key Benefits
- Obligate precursor to Coenzyme A - central to all energy metabolism
- Required for Krebs cycle (acetyl-CoA), fatty acid oxidation, and steroid synthesis
- Precursor to acyl carrier protein (fatty acid synthesis)
- Supports steroid hormone and CoQ10 biosynthesis
- 6mg = 100% NRV
The Research
Peer-reviewed human trials supporting this ingredient at this dose.
Pantothenic Acid (B5)
6mgCalcium pantothenate - pharmaceutical grade
Any time of day with food. Water-soluble - well-absorbed regardless of timing.