Why 2.8mg of Vitamin B2?

How Vitamin B2 works

Riboflavin is converted in the body to flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) - the flavin coenzymes required by the mitochondrial electron transport chain at Complexes I and II. These coenzymes carry electrons from NADH and FADH2 into the chain, driving the proton gradient that powers ATP synthase.

Critically, riboflavin is also required for glutathione reductase - the enzyme that regenerates reduced glutathione (GSH) from oxidised glutathione (GSSG). Without adequate FAD, the entire glutathione antioxidant cycle slows - directly linking riboflavin status to the effectiveness of the NAC and alpha-lipoic acid in this formula.

Key benefits

• Precursor to FMN and FAD - required for electron transport chain
• Enables glutathione recycling via glutathione reductase
• Required for fatty acid beta-oxidation
• Supports red blood cell production
• 1.4mg = 100% NRV

The researchGB-NHC

Peer-reviewed human trials supporting this ingredient at this dose.

1. Powers HJ. (2003). Am J Clin Nutr. 77(6):1352-60.Riboflavin (vitamin B-2) and health.PubMed →
2. Gnaiger E. (2024). J Biol Chem. 300(2):105663.Complex II ambiguities. FADH₂ in the electron transfer system.PubMed →
3. Bogataj Jontez N, et al. (2024). Nutrients. 16(11):1611.Does dietary supplement use increase micronutrient intake adequacy in healthy adults with habitual diets?PubMed →

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